Expanding the biological limits of degeneration of temporomandibular structures. Literature review

  • Jenny Fabiola Anchundia Reinoso Universidad Católica de Cuenca | Cuenca | Ecuador
  • Christian David Zapata Hildalgo Universidad Católica de Cuenca | Cuenca | Ecuador
  • Celia María Pulgarín Fernández Universidad Católica de Cuenca | Cuenca | Ecuador
Keywords: Temporomandibular joint; degeneration; biological limit; alterations; dysfunction.

Abstract

The temporomandibular joint (TMJ) is an essential structure that allows the jaw to open and close, and its degeneration can cause pain and dysfunction. This literature review begins by highlighting the importance of understanding all the underlying biological mechanisms of TMJ degeneration to develop better treatment approaches. This review aims to gather all the information on the molecular mechanisms, hormonal and genetic factors involved in signaling pathways and interactions that are potentially related to jaw disorders. The literature was selected by searching electronic databases. It was determined that in the face of an inflammatory and degenerative process of the TMJ, the presence of several proteins, molecules, hormones, and increased gene expression is present in large volume, however, future research with larger samples is needed to improve understanding in diagnostic and therapeutic approaches in this field.

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Author Biographies

Jenny Fabiola Anchundia Reinoso, Universidad Católica de Cuenca | Cuenca | Ecuador

Odontólogo General de la Universidad Católica de Cuenca, Especialista en Ortodoncia de la Universidad Católica de Cuenca.

Christian David Zapata Hildalgo, Universidad Católica de Cuenca | Cuenca | Ecuador

Odontólogo, especialista en Ortodoncia, docente en la Universidad Católica de Cuenca, Universidad Regional de los Andes, Universidad San Gregorio de Portoviejo. Práctica exclusiva en Ortodoncia, Socio Activo de la Sociedad de Ortodoncia del Azuay, Asociación Latinoamericana de Ortodoncia, Word Federation Orthodontic y de la Academia internacional de Odontología Integral

Celia María Pulgarín Fernández, Universidad Católica de Cuenca | Cuenca | Ecuador

Médico, Especialista en Medicina Crítica y Terapia Intensiva, Master en Administración de Empresas. Médico tratante de la Unidad de Pacientes Críticos Adultos del Hospital de Especialidades José Carrasco Arteaga. Cuenca, Ecuador. Miembro de la Sociedad Ecuatoriana de Terapia Intensiva núcleo Azuay.

References

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Published
2023-11-22
How to Cite
Anchundia Reinoso, J. F., Zapata Hildalgo, C. D., & Pulgarín Fernández, C. M. (2023). Expanding the biological limits of degeneration of temporomandibular structures. Literature review. Religación, 9(39), e2401126. https://doi.org/10.46652/rgn.v9i39.1126