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A segurança do paciente é um componente fundamental da qualidade assistencial; no entanto, persistem fragilidades na cultura de segurança, na gestão de riscos e na notificação de incidentes no primeiro nível de atenção. O objetivo deste estudo foi avaliar o impacto de uma intervenção educativa na gestão de riscos e na segurança do paciente em um consultório de atenção primária amazônica. Realizou-se um estudo de abordagem mista com delineamento quase-experimental pré-teste e pós-teste sem grupo controle. Participaram sete trabalhadores de saúde por meio de amostragem censitária. Aplicou-se um questionário tipo Likert validado (α = 0,82), complementado por entrevistas e observação. A intervenção baseou-se em metodologias ativas. Os resultados mostraram melhorias no conhecimento sobre riscos (14,3%) e na cultura de segurança e formação (28,6%). A análise qualitativa evidenciou menor medo da notificação e melhor comunicação. As limitações metodológicas sugerem cautela quanto à transferibilidade dos achados.
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